Review



isomer 3tc  (CEM Corporation)

 
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    CEM Corporation isomer 3tc
    Mechanism of antiviral action of 1,3-oxathiolane nucleosides, <t>3TC</t> ( 1 ) and FTC ( 2 ), as chain terminators.
    Isomer 3tc, supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/isomer 3tc/product/CEM Corporation
    Average 90 stars, based on 1 article reviews
    isomer 3tc - by Bioz Stars, 2026-03
    90/100 stars

    Images

    1) Product Images from "Synthetic strategies toward 1,3-oxathiolane nucleoside analogues"

    Article Title: Synthetic strategies toward 1,3-oxathiolane nucleoside analogues

    Journal: Beilstein Journal of Organic Chemistry

    doi: 10.3762/bjoc.17.182

    Mechanism of antiviral action of 1,3-oxathiolane nucleosides, 3TC ( 1 ) and FTC ( 2 ), as chain terminators.
    Figure Legend Snippet: Mechanism of antiviral action of 1,3-oxathiolane nucleosides, 3TC ( 1 ) and FTC ( 2 ), as chain terminators.

    Techniques Used:

    First synthesis of (±)-BCH-189 ( 1c ) by Belleau et al.
    Figure Legend Snippet: First synthesis of (±)-BCH-189 ( 1c ) by Belleau et al.

    Techniques Used:

    Enantioselective synthesis of 3TC ( 1 ).
    Figure Legend Snippet: Enantioselective synthesis of 3TC ( 1 ).

    Techniques Used:

    Synthesis of cis- diastereomer 3TC ( 1 ) from oxathiolane propionate 44 .
    Figure Legend Snippet: Synthesis of cis- diastereomer 3TC ( 1 ) from oxathiolane propionate 44 .

    Techniques Used:

    Synthesis of (±)-BCH-189 ( 1c ) via SnCl 4 -mediated N-glycosylation of 8 .
    Figure Legend Snippet: Synthesis of (±)-BCH-189 ( 1c ) via SnCl 4 -mediated N-glycosylation of 8 .

    Techniques Used:

    Synthesis of (+)-BCH-189 ( 1a ) via TMSOTf-mediated N-glycosylation of 20 .
    Figure Legend Snippet: Synthesis of (+)-BCH-189 ( 1a ) via TMSOTf-mediated N-glycosylation of 20 .

    Techniques Used:

    Synthesis of 3TC ( 1 ) from oxathiolane precursor 20a .
    Figure Legend Snippet: Synthesis of 3TC ( 1 ) from oxathiolane precursor 20a .

    Techniques Used:

    Synthesis of 3TC ( 1 ) via TMSI-mediated N-glycosylation.
    Figure Legend Snippet: Synthesis of 3TC ( 1 ) via TMSI-mediated N-glycosylation.

    Techniques Used:

    Enzymatic resolution of the monophosphate derivative 116 for the synthesis of (−)-BCH-189 ( 1 ) and (+)-BCH-189 ( 1a ).
    Figure Legend Snippet: Enzymatic resolution of the monophosphate derivative 116 for the synthesis of (−)-BCH-189 ( 1 ) and (+)-BCH-189 ( 1a ).

    Techniques Used:



    Similar Products

    isomer 3tc  (CEM Corporation)
    90
    CEM Corporation isomer 3tc
    Mechanism of antiviral action of 1,3-oxathiolane nucleosides, <t>3TC</t> ( 1 ) and FTC ( 2 ), as chain terminators.
    Isomer 3tc, supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/isomer 3tc/product/CEM Corporation
    Average 90 stars, based on 1 article reviews
    isomer 3tc - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    cis and trans 3tc isomers  (Daicel Chiral)
    90
    Daicel Chiral cis and trans 3tc isomers
    Mechanism of antiviral action of 1,3-oxathiolane nucleosides, <t>3TC</t> ( 1 ) and FTC ( 2 ), as chain terminators.
    Cis And Trans 3tc Isomers, supplied by Daicel Chiral, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cis and trans 3tc isomers/product/Daicel Chiral
    Average 90 stars, based on 1 article reviews
    cis and trans 3tc isomers - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    samples of 3tc isomers  (Daicel Corporation)
    90
    Daicel Corporation samples of 3tc isomers
    Mechanism of antiviral action of 1,3-oxathiolane nucleosides, <t>3TC</t> ( 1 ) and FTC ( 2 ), as chain terminators.
    Samples Of 3tc Isomers, supplied by Daicel Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/samples of 3tc isomers/product/Daicel Corporation
    Average 90 stars, based on 1 article reviews
    samples of 3tc isomers - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    1) and (2)3tc-tp isomers  (Dr Raymond Laboratories Inc)
    90
    Dr Raymond Laboratories Inc 1) and (2)3tc-tp isomers
    Mechanism of antiviral action of 1,3-oxathiolane nucleosides, <t>3TC</t> ( 1 ) and FTC ( 2 ), as chain terminators.
    1) And (2)3tc Tp Isomers, supplied by Dr Raymond Laboratories Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/1) and (2)3tc-tp isomers/product/Dr Raymond Laboratories Inc
    Average 90 stars, based on 1 article reviews
    1) and (2)3tc-tp isomers - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Mechanism of antiviral action of 1,3-oxathiolane nucleosides, 3TC ( 1 ) and FTC ( 2 ), as chain terminators.

    Journal: Beilstein Journal of Organic Chemistry

    Article Title: Synthetic strategies toward 1,3-oxathiolane nucleoside analogues

    doi: 10.3762/bjoc.17.182

    Figure Lengend Snippet: Mechanism of antiviral action of 1,3-oxathiolane nucleosides, 3TC ( 1 ) and FTC ( 2 ), as chain terminators.

    Article Snippet: Separation by chromatography and deprotection with TBAF in THF afforded the (−)-isomer 3TC ( 1 , EC50 = 0.07 µM in CEM cells) and the trans -isomer 1b .

    Techniques:

    First synthesis of (±)-BCH-189 ( 1c ) by Belleau et al.

    Journal: Beilstein Journal of Organic Chemistry

    Article Title: Synthetic strategies toward 1,3-oxathiolane nucleoside analogues

    doi: 10.3762/bjoc.17.182

    Figure Lengend Snippet: First synthesis of (±)-BCH-189 ( 1c ) by Belleau et al.

    Article Snippet: Separation by chromatography and deprotection with TBAF in THF afforded the (−)-isomer 3TC ( 1 , EC50 = 0.07 µM in CEM cells) and the trans -isomer 1b .

    Techniques:

    Enantioselective synthesis of 3TC ( 1 ).

    Journal: Beilstein Journal of Organic Chemistry

    Article Title: Synthetic strategies toward 1,3-oxathiolane nucleoside analogues

    doi: 10.3762/bjoc.17.182

    Figure Lengend Snippet: Enantioselective synthesis of 3TC ( 1 ).

    Article Snippet: Separation by chromatography and deprotection with TBAF in THF afforded the (−)-isomer 3TC ( 1 , EC50 = 0.07 µM in CEM cells) and the trans -isomer 1b .

    Techniques:

    Synthesis of cis- diastereomer 3TC ( 1 ) from oxathiolane propionate 44 .

    Journal: Beilstein Journal of Organic Chemistry

    Article Title: Synthetic strategies toward 1,3-oxathiolane nucleoside analogues

    doi: 10.3762/bjoc.17.182

    Figure Lengend Snippet: Synthesis of cis- diastereomer 3TC ( 1 ) from oxathiolane propionate 44 .

    Article Snippet: Separation by chromatography and deprotection with TBAF in THF afforded the (−)-isomer 3TC ( 1 , EC50 = 0.07 µM in CEM cells) and the trans -isomer 1b .

    Techniques:

    Synthesis of (±)-BCH-189 ( 1c ) via SnCl 4 -mediated N-glycosylation of 8 .

    Journal: Beilstein Journal of Organic Chemistry

    Article Title: Synthetic strategies toward 1,3-oxathiolane nucleoside analogues

    doi: 10.3762/bjoc.17.182

    Figure Lengend Snippet: Synthesis of (±)-BCH-189 ( 1c ) via SnCl 4 -mediated N-glycosylation of 8 .

    Article Snippet: Separation by chromatography and deprotection with TBAF in THF afforded the (−)-isomer 3TC ( 1 , EC50 = 0.07 µM in CEM cells) and the trans -isomer 1b .

    Techniques:

    Synthesis of (+)-BCH-189 ( 1a ) via TMSOTf-mediated N-glycosylation of 20 .

    Journal: Beilstein Journal of Organic Chemistry

    Article Title: Synthetic strategies toward 1,3-oxathiolane nucleoside analogues

    doi: 10.3762/bjoc.17.182

    Figure Lengend Snippet: Synthesis of (+)-BCH-189 ( 1a ) via TMSOTf-mediated N-glycosylation of 20 .

    Article Snippet: Separation by chromatography and deprotection with TBAF in THF afforded the (−)-isomer 3TC ( 1 , EC50 = 0.07 µM in CEM cells) and the trans -isomer 1b .

    Techniques:

    Synthesis of 3TC ( 1 ) from oxathiolane precursor 20a .

    Journal: Beilstein Journal of Organic Chemistry

    Article Title: Synthetic strategies toward 1,3-oxathiolane nucleoside analogues

    doi: 10.3762/bjoc.17.182

    Figure Lengend Snippet: Synthesis of 3TC ( 1 ) from oxathiolane precursor 20a .

    Article Snippet: Separation by chromatography and deprotection with TBAF in THF afforded the (−)-isomer 3TC ( 1 , EC50 = 0.07 µM in CEM cells) and the trans -isomer 1b .

    Techniques:

    Synthesis of 3TC ( 1 ) via TMSI-mediated N-glycosylation.

    Journal: Beilstein Journal of Organic Chemistry

    Article Title: Synthetic strategies toward 1,3-oxathiolane nucleoside analogues

    doi: 10.3762/bjoc.17.182

    Figure Lengend Snippet: Synthesis of 3TC ( 1 ) via TMSI-mediated N-glycosylation.

    Article Snippet: Separation by chromatography and deprotection with TBAF in THF afforded the (−)-isomer 3TC ( 1 , EC50 = 0.07 µM in CEM cells) and the trans -isomer 1b .

    Techniques:

    Enzymatic resolution of the monophosphate derivative 116 for the synthesis of (−)-BCH-189 ( 1 ) and (+)-BCH-189 ( 1a ).

    Journal: Beilstein Journal of Organic Chemistry

    Article Title: Synthetic strategies toward 1,3-oxathiolane nucleoside analogues

    doi: 10.3762/bjoc.17.182

    Figure Lengend Snippet: Enzymatic resolution of the monophosphate derivative 116 for the synthesis of (−)-BCH-189 ( 1 ) and (+)-BCH-189 ( 1a ).

    Article Snippet: Separation by chromatography and deprotection with TBAF in THF afforded the (−)-isomer 3TC ( 1 , EC50 = 0.07 µM in CEM cells) and the trans -isomer 1b .

    Techniques: